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Korean J Pancreas Biliary Tract > Volume 3(1):1998 > Article
The Korean Journal of Pancreas and Biliary Tract 1998;3(1):53-58.
변이형 점액성 췌장 낭선종 1예
류지곤1, 김용태1, 윤용범1, 김정룡1, 최국진2, 김우호3, 김용일3
1서울대학교 의과대학 내과학교실
2서울대학교 의과대학 외과학교실
3서울대학교 의과대학 병리학교실
A Case of Variant Type of Mucinous Cystadenoma of the Pancreas
Ji Kon Ryu1, Yong Tae Kim1, Yong Bum Yoon1, Chung Yong Kim1, Kuk Jin Choe2, Woo Ho Kim3, Yong Il Kim3
1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
2Department of Surgery, Seoul National University College of Medicine, Seoul, Korea
3Department of Pathology, Seoul National University College of Medicine, Seoul, Korea
Corresponding author:  Ji Kon Ryu,
ABSTRACT
The majority of pancreatic cystic lesions are benign pseudocysts, but 10-15% are ultimately proven to be cystic neoplasms. Serous cystadenoma and mucinous cystic neoplasm are the most common cystic neoplasms of the pancreas. Serous cystadenoma is benign and has a characteristic spongy gross appearance as a result of numerous microcysts. The individual cysts are lined by flat to cuboidal, clear to pale epithelial cells rich in glycogen. Mucinous cystic neoplasm has a potential to malignancy and consists of large macrocysts. Histologically, mucinous cystic neoplasms are lined with columnar epithelia containing intracellular mucin. In this report, we describe a rare type of cystic neoplasm of the pancreas arising in a 77-year-old woman who complained of a palpable abdominal mass. A distal pancreatectomy and splenectomy were done. The tumor was found to be a mixed pattem of macrocyst and microcyst and measured 7 x 5 x 3 cm. The lining cells were mainly composed of columnar cells which were positive for mucicarmine staining, but cuboidal cells which suggested serous cystadenoma were also noticed in some areas. The cuboidal cells were negative for mucicarmine but PAS stains did not disappear with diastase. Neither cellular atypism nor dysplasia were found. To the best of our knowledge, this is the first case ever reported of a variant type of mucinous cystic neoplasm which is grossly mixed macrocystic and microcystic and consists of two kinds of epithelial cells, one columnar and the other cuboidal.
Keywords: Cystic neoplasm of pancreas, Mucinous cystic neoplasm
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